Ayurvedic Management of Primary Hypothyroidism with Integrated Medicine and Pranayama Therapy: A Single Case Report

Abstract

Primary hypothyroidism is a common endocrine disorder characterized by inadequate thyroid hormone production and raised thyroid stimulating hormone (TSH), resulting in metabolic slowing and systemic manifestations. In Ayurvedic clinical practice, such presentations are commonly interpreted through the lens of Agnimandya, Kapha-Vata predominance, Medodushti, and Srotorodha (Obstruction of the microchannels), and management is planned to restore metabolic balance and channel patency. A 35-year male patient, presented with diagnosed primary hypothyroidism and with elevated serum TSH. The baseline laboratory report dated 18 July 2025 documented TSH-Ultrasensitive 15.9 µIU/mL with laboratory reference interval 0.54-5.30 µIU/mL. The patient was managed with an integrated Ayurvedic regimen consisting of Sarvakalp Kwath 50 mL twice daily, Thyrogrit Vati 2 tablets twice daily with coriander chutney as anupana, Kanchanar Guggulu 500mg , Arogya Vardhini Vati 250 mg 2-2  tablets twice daily, and Ujjayi Pranayama 20 repetitions twice daily before meals. Follow-up thyroid profile dated 25 August 2025 showed T3 1.08 ng/mL, T4 11.78 µg/dL, and TSH 5.38 µIU/mL with laboratory reference interval 0.34-5.60 µIU/mL [image:2]. This corresponds to an approximate 66.2% reduction in TSH from baseline. Marked biochemical improvement was observed within one month, and the patient also reported symptomatic relief during follow-up. This single case report indicates that a structured Ayurvedic management protocol combined with pranayama may offer clinical benefit in primary hypothyroidism. Further systematic studies with larger samples and longer follow-up are required to evaluate safety, reproducibility, and long-term effectiveness.